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In this video, Veronica from the Michigan Medical School's Office of Research explains the key aspects of cooperative agreement funding mechanisms, specifically NIH U-type grants. She highlights the significant role that funding agency staff play in these agreements, which differ from typical grant funding like NIH R-type grants. Understanding these differences is crucial for applicants. The primary aim of cooperative agreements is to support investigator-driven research, meaning that agency staff engage more actively in both scientific and administrative aspects compared to standard grants. Throughout the presentation, she will reference NIH cooperative agreements to illustrate these points.