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Early-onset knee osteoarthritis is commonly observed after ACL reconstruction, and may be attributable to residual abnormal joint mechanics following surgery. Graft tunnel placement is a surgical factor that may affect internal knee joint mechanics, and thereby joint health. In this study, researchers from the University of Wisconsin used a combination of MRI and computational modeling to assess the consequences of graft placement on the loading of cartilage in the knee. The findings, reported in the American Journal of Sports Medicine, highlight the aspects of graft placement that surgeons should most closely consider to restore normal mechanics during ACL reconstruction. MRI measurements were performed to assess the ACL tunnel location and graft angle in the knees of 18 participants who had undergone ACL reconstruction. A clinical laxity test was performed on each subject following the completion of post-surgery physical therapy. Dynamic MRI was used to measure tibiofemoral kinematic