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Blotz are molecular biology techniques that detect specific nucleotide or protein sequences in a sample. Southern blot detects DNA sequences, northern blot detects RNA for gene expression, and western blot detects proteins using specific antibodies. The process involves separating DNA or proteins on a gel, transferring them to a filter, and applying labeled probes for visualization. Southern and northern blot use DNA probes, while western blot uses protein-specific antibodies for detection.