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Hi, this is Svenja Lohner from Science Buddies, and this video is an introduction to how to use the free online BLAST tool from the NCBI website (National Center for Biotechnology Information) for your genomic research. BLAST stands for Basic Local Alignment Search Tool and is a computer algorithm that identifies similarities between biological sequences by comparing nucleotide or protein sequences to a database of sequences. You can get to the BLAST website from the NCBI main homepage by clicking on the BLAST link under Popular Resources on the right, or by searching for the tool in your web browser and clicking on the BLAST website link. When you get to the BLAST main page, you will see different BLAST options. You can do a nucleotide BLAST which compares nucleotide sequences. This is useful when trying to determine the evolutionary relationships among different organisms. The protein BLAST compares protein sequences and is useful when trying to identi