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all right good afternoon iamp;#39;m julia chill from fda office of study integrity and surveillance and the talk of the title of my talk is going to be blinding during bio-equivalence trials so you may be wondering why specifically am i talking about blinding during biological trial i think thatamp;#39;s a very good question whatamp;#39;s special about it so in order to answer the question we need to first out find out what the bio equivalence trials are so let me ask one question here how many of you are you here are familiar with bio equivalence or biological studies thatamp;#39;s great some reason people on this side have more exposure than this side so maybe i should turn this way to start talking about well so iamp;#39;m going to just introduce my agenda which iamp;#39;m going to start with what is about recovering trial and i think that would be helpful for the people who hasnamp;#39;t been exposure to that and how the blinding codes play a role in bioequivalence studies t