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so the printamp;#39;s a little smaller here but um the font uh but Iamp;#39;m going to present the results of the ecog Akron e1910 National clinical trials Network clinical trial this is a phase three randomized trial of linatumumab for newly diagnosed BCR able negative we also refer to the BCR able Gene rearrangement as a Philadelphia chromosome so these patients were negative for this finding but they had B lineage acute lymphoblastic leukemia kilenophoblastic leukemias is the acute leukemia counterpart of what Dr Brown just told you about with chronic lymphocytic leukemia and these are the cells that we worry about these are the blast cells that donamp;#39;t function well and cause these patients to develop infections and bleeding and can be fatal if not treated so the molecule we were testing is blinnatumamab this is a bi-specific T-cell engager molecule you can see on the left that it combines the variable region of two antibodies one directed against the cd19 which is on the l