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In this video tutorial series titled "Pyrotechnics Explained in Five Minutes," the host introduces the concept of Western blotting, a crucial technique in biology. Western blotting allows for the detection of a specific protein within a mixture of proteins, making it a widely utilized diagnostic tool for various infectious diseases, including HIV. The video highlights the technique's significance in both fundamental research and clinical diagnostics. The process begins with taking a cell lysate or protein extract and separating the proteins by molecular weight using SDS-PAGE gel. Further details about the procedure and its applications will be discussed later in the video.