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Dr. Niraj discusses dot blot and slot blot hybridization techniques in this video tutorial. These techniques are used to identify, quantify, and determine the concentration of DNA, RNA, or proteins in a sample without the need for restriction digestion or electrophoresis. By applying the sample directly to a membrane, a particular molecule can be detected. Dot blot and slot blot techniques are named based on the shape in which the sample is blotted on the membrane.