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one of the big things thatamp;#39;s came out that came out recently and something that weamp;#39;re so excited about because itamp;#39;s not often that you got a huge break that you get a huge breakthrough with docHub improvement and patience to see status specifically in ovarian cancer but the PARP inhibitors really have created its whole own world of treatments and management initially we thought it was really limited to BRCA mutated patients but thereamp;#39;s been more and more studies that came out that demonstrate that thereamp;#39;s efficacy in patients who donamp;#39;t necessarily have the brackla mutation but they have whatamp;#39;s called who are HIV positive or recombination deficient patients that has efficacy in those patients or even some studies that show that patients who are non BRCA non ahrd also have benefit from PARP inhibitors