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Heart failure is when the heart cannot supply enough blood to meet the body's demands. This can happen as systolic heart failure, when the ventricles can't pump blood hard enough, or diastolic heart failure, when not enough blood fills the ventricles. This leads to congestion or fluid buildup in the lungs, known as congestive heart failure (CHF). It affects millions globally and can result in death. Heart diseases like ischemia and valvular disease can impair the heart's ability to pump blood, leading to heart failure. Systolic heart failure involves the ventricles not pumping blood hard enough.