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On a Saturday at noon, the narrator describes the aftermath of a night of drinking, highlighting that over half of college students experience blackouts, which differ from passing out. The text explains the process of memory formation: normally, the prefrontal cortex records experiences in short-term memory, and the hippocampus organizes them into long-term memory. This allows individuals to recall entire events rather than isolated details. However, the ability to store these memories is disrupted by alcohol, which inhibits the neurotransmitters necessary for long-term memory formation.