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On Saturday at 12 p.m., the narrator describes a scenario where one may experience a headache and memory loss from the previous night, pointing out that over half of college students encounter blackouts. It clarifies that blacking out differs from passing out; individuals are often awake but cannot remember the events. The brain's prefrontal cortex usually stores experiences in short-term memory, which the hippocampus then organizes into long-term memories. However, alcohol consumption interferes with neurotransmitters that are essential for forming these long-term memories, leading to gaps in recollection the following day.