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In this video blog, Joe Riley, president of National Drug Screening, discusses drug testing related to cut-off levels and detection times. He explains that drug tests analyze urine or hair specimens for drug metabolites, which are the substances the body produces after processing drugs. A positive test occurs when the metabolite levels exceed specified cut-off levels set by laboratories, while levels below these thresholds result in a negative outcome. The video touches on how different drugs have varying cut-off levels to ensure accurate results.