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[Music] guru nation hows it going just uh got out of a meeting with one of my doctors that video is coming up soon with a pi perspective of a newer pi newer on the site side but not new on the sponsor side uh i got a question what is a database lock and why is it so stressful so the answer is a database lock is when the sponsor uh periodically reviews the data from the study to make a decision on the safety and efficacy so they literally decide do we continue this study at the extremes or not or do we need to modify the protocol or do we need to pay more attention to certain saes what do we need to do thats a database lock its usually done every quarter and its done to give the sponsors more insight into like real time into how the study is progressing now why is this database lock uh stressful its stressful for a number of reasons stressful on the site side on the sites perspective meaning you know the coordinators need to answer all the queries in the edc and they need to make