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one of the most standardized way of handling mice is picking them up by the tail and scruffing them for various procedures just remove the C carefully catch the Animal by the tail pre probably at the base of the tail but in mice which are very small animals you can also take them further out you pick the mouse up and place her on a secure surface either your hand or for instance on a catlet allow the animal to get a grip before you Scruff her then you take a lot of skin as much as you can get you turn the animal around catch the tail with your little finger and hold the animal like this then you have a secure grip and you can do various procedures for instance urine sampling or injections when youamp;#39;re done you put the mouse back either on the surface or back in the cage