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In the 1930s, the United States was ravaged by syphilis. This sexually transmitted infection afflicted nearly 1 in 10 Americans, producing painful sores and rashes that persisted for roughly two years. After these initial symptoms, late-stage syphilis was known to cause organ damage, heart and brain disorders, and even blindness. It was incredibly difficult to slow the diseases spread. Experts cautioned against unprotected sex, but the infection could also be passed during childbirth. Worse still, existing treatments like mercury and bismuth were considered unreliable at best and potentially harmful at worst. Today these heavy metals are classified as toxic, but at the time, doctors were still uncovering their dangerous side effects. Amidst the uncertainty, health care professionals had two key questions. Did late-stage syphilis warrant the risks of existing treatments? And, did the infected individuals race change how the disease progressed? Many physicians were convinced syph
