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blood-alcohol concentration or BAC refers to the amount of alcohol present in the bloodstream measured by the weight of ethanol and grams per 100 milliliters of blood blackouts occur when the alcohol level in the blood docHubes point two which on average is about four drinks for women and five for men to understand how we need to first look at memory consolidation in the hippocampus short-term memories are converted into long-term ones through the persistent strengthening of the synapses a process known as long-term potentiation these synapses pass signals through neurotransmitters like glutamate and gamma amino butyric acid or GA PA for a signal to fire the receiving neuron must have a higher positive charge glutamate binds to neural receptors and opens it for positive ions triggering signal firing GA PA meanwhile allows a negative ions which momentarily blocks this action alcohol increases GA PA activity causing it to inhibit signals more often and longer than usual this prolonged dep