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hello everyone welcome to 10 minute physiology in todayamp;#39;s video weamp;#39;re going to talk about how certain types of hormones and neurotransmitters control vascular tone so with that letamp;#39;s begin so iamp;#39;d like to start off by first talking about how vascular smooth muscle cells contract in the first place so this right here is the plasma membrane of a vascular smooth muscle cell and weamp;#39;re when weamp;#39;re talking about the contraction of vascular smooth muscle cells weamp;#39;re usually going to talk about three ways in which contraction can occur so the first way in which vascular smooth muscle cell contraction can occur is of course through increasing the calcium level so when we increase calcium this causes calcium to bind to a protein called calmodulin so when four calciums bind to calmodulin the calcium calmodulin complex will go interact with another protein called myosin light chain kinase so myosin light chain kinase is a kinase protein
