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foreign and Iamp;#39;m an assistant professor in the department of pharmacology at the University of North Carolina at Chapel Hill Iamp;#39;d like to start off by thanking the organizers for inviting me to speak today and Iamp;#39;m excited to share some of our science with you today Iamp;#39;m going to be speaking to you about inhibiting the raspathway as a treatment approach for pancreatic cancer I wanted to start with a brief introduction to this pathway there are three rafts isoforms k-ras and Ras and hras as a family these mutations mutations in these proteins Drive about 25 percent of human cancers K Ross is mutated primarily in pancreatic cancer and that will be the topic of our discussion today the pathway Downstream of k-ras that I will focus on is the Wrath Mech ERC pathway some of the cancers with the highest frequencies of rasputations are pancreatic colorectal and lung adenocarcinoma and when we look at cancer-associated deaths in the U.S these three cancers ar
