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hello and welcome to the nanomedicine lecture on targeting so first of all weamp;#39;re going to talk about active versus passive targeting and targeting in general so why would you ever want to target something weamp;#39;ve already talked about in class about the enhanced permeability and retention or the EPR effect where tumors or other things can accumulate nanoparticles just passively there into the tumor and so why would you actually want to target and what is targeting so targeting is putting a ligand onto a nanoparticle that will specify the nanoparticle to go one place or the other so this allows you to increase specificity of the nanoparticle so in that way you can get tumor versus normal or you can get one cell type versus the other cell type now mind you this doesnamp;#39;t itamp;#39;s not binary itamp;#39;s not on or off you can just change the distribution by a little bit and Iamp;#39;ll show you examples of this later in the lecture with targeting you can change bio