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In this lecture we re gonna cover the pharmacology of drugs used in treatment of heart failure, so let s get right into it. Heart failure is simply defined as a chronic, progressive disorder in which the heart muscle is unable to pump enough blood to meet the bodys needs. In a normal heart, the upper chambers called the atria and the lower chambers called the ventricles squeeze and relax in turn to move blood through the body. Now blood flows through the heart and lungs in four major steps. First, the oxygen-poor blood that has already circulated through the body is received by the right atrium, which in turn pumps it over to the right ventricle. Secondly, the right ventricle pumps the blood through the pulmonary artery into the lungs, where it picks up oxygen. Thirdly, the pulmonary vein empties oxygen-rich blood, from the lungs into the left atrium, which in turn pumps it to the left ventricle. And finally the left ventricle pumps oxygenated blood through the aorta to the rest of t
