Bind motif in pdf

Aug 6th, 2022
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How to bind motif in pdf

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thank you hi everyone welcome back to my channel I am so happy to see you all here so in this video we are going to talk about some of the downstream analysis that we can perform with certain types of high throughput data and we will be talking about that in further detail but the highlight of todayamp;#39;s topic is going to be motive Discovery and Performing transcription Factor binding site analysis looking for transcription Factor binding sites looking for motives but before we go into that we are going to talk about what are motives what are transcription factors um how do transcription Factor regulate or control the expression of genes how are these motifs represented uh more importantly what kind of questions uh do transcription Factor binding site analysis help to answer and lastly I would also want to perform a demonstration using one of the tool that is freely available online I would want to perform motive Discovery and also answer some specific questions um with re

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Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein. Domains may exist in a variety of biological contexts, where similar domains can be found in proteins with different functions.
Although each of these proteins has unique features, most bind to DNA as homodimers or heterodimers and recognize DNA through one of a small number of structural motifs. The common motifs include the helix-turn-helix, the homeodomain, the leucine zipper, the helix-loop-helix, and zinc fingers of several types.
Answer: A motif is a chain-like biological structure made up of connectivity between secondary structural pieces, whereas a domain is a three-dimensional protein structures independent folding unit.
Listen to pronunciation. (doh-MAYN) A specific physical region or amino acid sequence in a protein that is associated with a particular function or corresponding segment of DNA.
Usually, interaction with the sugarphosphate backbone of the DNA molecules is nonsequence-specific. The helixturnhelix (HTH) motif is the most common motif found in DNA-binding proteins in both prokaryotes and eukaryotes.
Transcription factor binding motifs (TFBMs) are genomic sequences that specifically bind to transcription factors. The consensus sequence of a TFBM is variable, and there are a number of possible bases at certain positions in the motif, whereas other positions have a fixed base.
The difference between an archetype and a motif is that an archetype is a universal idea or symbol that occurs across multiple literary works while a motifs significance is specific to the thematic development of one particular literary work.
Protein motifs are small regions of protein three-dimensional structure or amino acid sequence shared among different proteins. They are recognizable regions of protein structure that may (or may not) be defined by a unique chemical or biological function.

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