Bind motif in NEIS

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How to bind motif in NEIS

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thank you hi everyone welcome back to my channel I am so happy to see you all here so in this video we are going to talk about some of the downstream analysis that we can perform with certain types of high throughput data and we will be talking about that in further detail but the highlight of todayamp;#39;s topic is going to be motive Discovery and Performing transcription Factor binding site analysis looking for transcription Factor binding sites looking for motives but before we go into that we are going to talk about what are motives what are transcription factors um how do transcription Factor regulate or control the expression of genes how are these motifs represented uh more importantly what kind of questions uh do transcription Factor binding site analysis help to answer and lastly I would also want to perform a demonstration using one of the tool that is freely available online I would want to perform motive Discovery and also answer some specific questions um with re

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What are protein motifs and their functions?

A motif is a short conserved sequence pattern associated with distinct functions of a protein or DNA. It is often associated with a distinct structural site performing a particular function. A typical motif, such as a Zn-finger motif, is ten to twenty amino acids long.

What are protein sequence motifs?

Protein sequence motifs are signatures of protein families and can often be used as tools for the prediction of protein function. The generalization and modification of already known motifs are becoming major trends in the literature, even though new motifs are still being discovered at an approximately linear rate.

What type of motif is found in domains that bind to DNA?

The helixturnhelix (HTH) motif is the most common motif found in DNA-binding proteins in both prokaryotes and eukaryotes. This motif contains about 20 amino acids that form two helices and a short four-residue turn in between (Figure 1a).

What are binding motifs for transcription factors?

Transcription factor binding motifs (TFBMs) are genomic sequences that specifically bind to transcription factors. The consensus sequence of a TFBM is variable, and there are a number of possible bases at certain positions in the motif, whereas other positions have a fixed base.

What are the motifs that can bind DNA?

Although each of these proteins has unique features, most bind to DNA as homodimers or heterodimers and recognize DNA through one of a small number of structural motifs. The common motifs include the helix-turn-helix, the homeodomain, the leucine zipper, the helix-loop-helix, and zinc fingers of several types.

What are three structural motifs that are commonly found in DNA binding proteins?

Focus on Relevant Research. Many motifs are involved in the binding of DNA. These motifs include the helix-turn-helix (HTH), helix-loop-helix (HLH), zinc fingers, and leucine zippers. The associated paper focuses on the roles of the HLH motif of Mre11.

What are the motifs for RNA binding proteins?

The RNA-recognition motif (RRM), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain) is the most abundant RNA-binding domain in higher vertebrates (this motif is present in about 0.5%-1% of human genes)3 and is the most extensively studied RNA-binding domain, both in terms of structure and

What are the binding motifs in proteins?

A binding motif pair consists of two motifs each derived from one side of the binding protein sequences. The discovery is a directed approach that uses a combination of two data sources: 3-D structures of protein complexes and sequences of interacting proteins.

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