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hi Iamp;#39;m dr. Zoe Walla and Iamp;#39;m a lecturer in chemical biology in the School of Pharmacy at UVA the aim of this video is to explain our recent research to a general audience itamp;#39;s just been published in organic and biomolecular chemistry the article is open access so you donamp;#39;t need a subscription to read it the lengthy article is on the youtube web page the title of the work is identification of new DNA emotive binding ligands through a fluorescent insulator displacement assay the work is about a special type of DNA structure called the I motifs or C cut effects this structure is different to the typical twisted ladder B form double helix which was first proposed by Watson and Crick in 1953 itamp;#39;s been shown that compounds that bind emotive structures can help switch genes on or off so it could be used to target genetic diseases such as cancer or diabetes this work describes using a fluorescence assay to find new compounds to bind this DNA structure we