Bind motif in binary

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Aug 6th, 2022
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How to bind motif in binary

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and yeah thank you very much for having me itamp;#39;s a pleasure to be here and Iamp;#39;m happy to present to you some work in our lab on computational welding of protein RNA interaction so antibiotic proteins are involved in pretty much every aspect of prostitutional Regulation so this starts at transcription already over to splicing export of rnas to the cytoplasm localization of rnas of course translation and also degradation of rnas so in this talk I will mention a lot proteins binding to rnas proteins buying transcripts proteins binding to specific sites but of course device Works was also true so one can equally argue that rnas are also acting on ibps in order to recruit them to for example a stiffness stabilizing factors for this talk I will take the few of rbps binding or acting on RNA molecules foreign binding of proteins to RNA and Vivo and one thatamp;#39;s um well in recent years very popular because it has high spatial resolution of the binding sites is clipsic or der

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Transcription factor binding motifs (TFBMs) are genomic sequences that specifically bind to transcription factors. The consensus sequence of a TFBM is variable, and there are a number of possible bases at certain positions in the motif, whereas other positions have a fixed base.
Sequence motifs are short, recurring patterns in DNA that are presumed to have a biological function. Often they indicate sequence-specific binding sites for proteins such as nucleases and transcription factors (TF).
In general, proteins bind to DNA in the major groove; however, there are exceptions.
These motifs generally use either helices or sheets to bind to the major groove of DNA; this groove, as we have seen, contains sufficient information to distinguish one DNA sequence from any other.
These proteins bind to regions of DNA, called regulatory elements which are located near promoters. The promoter is the region of a gene where RNA polymerase binds to initiate transcription of the DNA to mRNA. After regulatory proteins bind to regulatory elements, the proteins can interact with RNA polymerase.
The helixturnhelix (HTH) motif is the most common motif found in DNA-binding proteins in both prokaryotes and eukaryotes. This motif contains about 20 amino acids that form two helices and a short four-residue turn in between (Figure 1a).

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