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you my name is Catherine Warrick and Iamp;#39;m an application scientists working with BMG lab tech for the the UK division Iamp;#39;m very lucky to be joined today for this sls workshop by Professor Steven Charlton Stephan has a vast experience from his time at Novartis but heamp;#39;s now heading up accelerate vo and also is a professor at the University of Nottingham also from the UK so today together weamp;#39;re going to be introducing to you the use of tag lights HRF probes for the measurement of kinetic interactions before I pass over to Steven who is the person everybodyamp;#39;s here to really talk about his work with fragment screening in this area Iamp;#39;d like to just talk a bit about the fairest RFS X that is used by Stephen and his team in their labs and some of the features that really make the fairest are applicable for this kind of kinetic monitoring using TR for applications so a lot of people here will perhaps already have a ferrous RFS in their laboratory ev