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in that this is largely organized by the center administrators and i particularly want to thank liz leverens our administrator for making this happen um i think everybody knows the talks are on youtube and so uh for those who cant listen in lifetime zoom um you can refer to youtube to listen to these talks that are presented today so im going to be introducing the two speakers theyre going to have 20 minutes to talk theyll be a 10 minute q a session and we believe we have the ability to extend that q and a session beyond 5 oclock we should end at 5 but if there are lingering questions um you can ask them through the q a option our first speaker is mitch oconnell he is an assistant professor in the department of biochemistry and biophysics mitch obtained his phd degree from the university of sydney in new south wales australia and then he did postdoctoral work with jennifer doudna at uc berkeley he uh joined the uh now i can see myself he joined the university of rochester in 201