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all right welcome to the enzyme kinetics series of videos this video is part two of a two-part series on ligand binding and the adair model now in part one I talked about the relationship between the macroscopic and dissociation constants and the microscopic dissociation constants in terms of the number of binding sites excuse me and the number of ligands this one here is just the reciprocal of this - in terms of the association constants instead of the dissociation constants so weamp;#39;re going to use some of these results and some of the concepts in part two so I would review that video if you havenamp;#39;t seen that video let me excuse me let me motivate us a bit so here we have a picture of hemoglobin as you know hemoglobin is responsible for carrying oxygen in the bloodstream picks it up in the lungs and then dumps it in the tissues and then returns back to the lungs for to pick up more oxygen so this is a picture of the protein molecule itself it has four subunits thereamp;
