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so today Iamp;#39;m going to talk about molecular insight into new opioid deactivation and this is the work that we did in Stanford University in panda lab in chemistry so the content of my talk is actually distributed among two topics the first one is the MU or the activation and Lagaan induced feed which Iamp;#39;m going through some kind of nice things about the activation processes and the activation of the receptor and another one is one of the challenging questions that we are addressing about the binding pathway of the drug to the receptor why I mean mu opioid receptors are important because itamp;#39;s one of the oldest actually drug targets in pharmacopoeia and people actually try to design drugs I mean which are like analgesics which can basically set eight I mean theyamp;#39;re ours like tylenol actually bind to this receptor and they are just creating a kind of downward cascade inside the cell as you can see the the morphine I mean which is a classical type of opioid is