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Pre-workout supplements are popular for enhancing performance through mental stimulation, delaying muscle fatigue, and providing an energy boost during training. Ed Whittaker, a performance nutritionist, emphasizes the importance of proper nutrition before considering these supplements. He advises consuming a carb-rich meal about two hours prior to workouts to ensure sufficient energy levels, as inadequate nutrition can hinder performance. Overall, while pre-workouts can be effective, they should complement a solid nutritional foundation for best results.