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Hello, I am Marina DiStefano, a clinical molecular genetics fellow at Harvard and postdoc in the ClinGen Resource. This tutorial is part 1 of a series on transcript annotation and curation. Part 1 covers why transcript curation is important, with examples from the hearing loss domain. It also discusses different transcript annotation bodies. Parts 2 and 3 will delve into resources and strategies for transcript curation. Gene curation is necessary for variant curation, as the impact of a variant on a gene depends on its disease association.
