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all right is that coming through yep looks good eric welcome everyone so uh as benj ben mentioned im at the lawrence livermore uh biofuels sfa project uh and this is a project that uh weve been doing in collaboration with sort of the uh the livermore team there uh especially with jeff kimbrough whos been my partner in crime on developing these uh tools for k base and also in collaboration very closely with chris henrys team at argonne and so the topic for today is on integrating third-party functional annotation tools uh to do metabolic modeling in k base so you probably all know the whole genome metabolic modeling has turned out to be one of these cornerstone techniques in systems biology because it really allows us to go directly from a genome sequence to saying something about what what that organism might be doing with that genome and theres very few techniques that allow you to make that giant leap um but how do we even know that the underlying metabolic network were workin