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Health technology assessments (HTAs) systematically evaluate the clinical, economic, and social implications of healthcare technologies, including drugs, medical devices, and diagnostic tests. They inform decision-making regarding the adoption and use of these technologies. HTA involves reviewing evidence on safety, efficacy, and cost-effectiveness, while also considering patient outcomes, ethical issues, social implications, and implementation feasibility. Various stakeholders, such as policymakers, healthcare providers, and patients, utilize HTAs to guide decisions and improve healthcare practices. This channel is sponsored by Nested Knowledge, a platform that supports systematic literature reviews and meta-analyses.