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5.4 million Americans suffer from heart failure a debilitating and progressive disease that impedes the hearts ability to pump sufficient blood to the bodys organs one of the things that puts individuals at greater risk for cardiovascular disease and heart failure is a deficiency in vitamin D we asked simply the question how does vitamin D affect heart and cardiovascular functions and over these decades what weve shown is theres dramatic and very important effects weve shown that cardiac hypertrophy or just enlargement of the heart occurs in vitamin D deficiency vitamin D that you would get at your local drugstore is useful for treating vitamin D deficiency and that is important but it doesnt relate to our research we know that vitamin D deficiency can result in cardiovascular disease but the kind of therapeutic that were interested in developing is much more potent than vitamin D and would be effective even in an individual who has a normal vitamin D we believe at this point f