Adapt spot in AFP

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Aug 6th, 2022
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How to adapt spot in AFP

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AFP is measured in nanograms per milliliter (ng/mL), with normal levels less than 20 ng/mL. Levels above 400 ng/mL may indicate a liver tumor or other cancer. Elevated levels of AFP may indicate cancer of the liver, ovaries or testicles, but that isnt always the case.
Introduction: serum alpha-fetoprotein (AFP) was routinely employed as a tumor marker for screening, diagnosis, and treatment follow-up of hepatocellular carcinoma (HCC). However, a substantial proportion of HCC patients had normal AFP level even at an advanced disease status.
A very high level of AFP or a sudden increase can be an early sign of liver cancer. Most medical experts dont recommend measuring AFP levels to screen for cancer in these diseases. But, some health care providers may still use an AFP tumor marker test with other tests to watch for liver cancer.
The study by Harada T, et al. [39] showed that approximately 40% of all cirrhotic patients will have AFP levels higher than 20 ng/ml. An increase in AFP levels (between 10 and 500 ng/ml, and sometimes up to 1000 ng/ml) can be seen in adult patients with hepatitis or cirrhosis with any etiology.
An AFP tumor marker test is a blood test that measures the level of AFP (alpha-fetoprotein) in a sample of your blood. Its usually used to help diagnose certain types of cancer and to check how well treatment is working. AFP is a protein that the liver makes when its cells are growing and dividing to make new cells.
Alpha fetoprotein When elevated, the AFP is 75-91% specific, and values greater than 400 ng/mL are generally considered diagnostic of HCC in the proper clinical context, including appropriate radiologic findings. (See Table 2 below.) Better biologic markers, including AFP variants, are being investigated.
AFP levels in men and non-pregnant women vary by age and race but typically range from 0 to 40 ng/mL. Maternal AFP levels increase during pregnancy from about the 14th week of gestation until about 32 weeks. Between 15 and 20 weeks, AFP levels typically range between 10 and 150 ng/mL.

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