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at this ash meeting the long-term follow-up of the rattle tile had been presented by providing new insights in to the efficacy of the response adapted treatment for advanced stage article informal patient the trial has now achieved seven year follow-up results and with the 121 patient enrolled and treated ing to the study the data were very well seen and taken the randomized part as you may recall of the study was the dedicated to Patient achieving a complete response after two cycles of ABD and was the final used ing to pet that was David score one two three this patient were randomized to receive abvd or ABD without volumizing and the initial results were consistent with non-inferiority between the two the two regiments and at seven here again the new inferiority was confirmed but in terms of progression for survival and overall survival with the excellent the results that without any additional signals in terms of safety for the positive part of the rattle trial which was a non-rand