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[Music] seven years ago the glaucoma Research Foundation put together four of us to achieve an ambitious goal of figuring out how we can better measure glaucoma make new biomarkers so that we can better diagnose disease and better determine whether patients are progressing or getting worse its been an amazing seven years weve made advances in the basic science of understanding glaucoma and importantly weve made advances in engineering new ways to measure the disease in our patients right now we are in the midst of clinical studies to validate these biomarkers and to see how well they predict changes in glaucoma this catalyst for a Cure team early on discovered that the inputs of the ganglion cells the dendrites of the ganglion cells have very early changes in glaucoma and pinpointed a specific layer or specific type of ganglion cell that has the earliest changes weve identified mitochondrial signatures that are indicative of ganglion cell dysfunction that hold the potential to be i
