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[Music] foreign [Music] Hello everybody welcome back to virology today were going to finish talking about how virus infected cells produce viral nucleic acids weve talked about RNA viruses weve talked about DNA viruses and now were going to talk about RNA viruses where there is a DNA intermediate and well talk about reverse transcription the process of making DNA from RNA and integration and maybe youve noticed in my lectures I have a quote on the first slide this is one of my favorites from Alice in Wonderland I one cant believe in possible things said Alice I dare say you havent had much practice said the queen why sometimes Ive believed as many as six impossible things before breakfast kind of encapsulates todays subject retroviruses were once called tumor viruses in 1908 and 1911 two separate discoveries of viruses that could cause cancers first the discovery 1908 of chicken leukemia virus and 1911 the discovery of arous sarcoma virus and we will talk about these later w