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Motor Neurone Disease (MND) affects about 5,000 people in the UK at any given time. It refers to a group of conditions that impact motor neurons—nerves in the brain and spinal cord responsible for sending messages to muscles, which can lead to weakness, loss of movement, and muscle wasting. Early symptoms may include mild weakness, clumsiness, tripping, or slurred speech, but experiences vary widely among individuals, making diagnosis challenging. There are no definitive tests; diagnosis typically involves ruling out other conditions and monitoring symptom progression, which can take time. Currently, there is no cure for MND, and it is life-shortening, but specialist support and social care assessments can help manage symptoms and improve quality of life.