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thank you for the opportunity to present some of the work were doing with biomaterials down in Cape Town most of what Ill talk about is related to myocardial infarction therapy but Ill also discuss some other stuff that we do with these Pig with these type our type of biomaterial so Im sure for most this audience I dont have to say this but clearly myocardial infarction and juice heart failure is a docHub problem these costs are seen here the social costs to twenty forty percent mortality in one year and this is I think this is from a few years back in the u.s. era and the economic costs are staggering and clearly we need additional alternative therapies very briefly in one slide to try and encapsulate what we targeting in in in myocardial infarction therapy for for heart failure is trying to derange this situation which happens in certain hearts that undergo michael infarction you get expansion of the in fact and that can then go on to pathological remodeling the heart beco