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- [Narrator] The default mode network activates when a person is introspective and under normal circumstances becomes less active when a person shifts their attention to the outside world. But brain studies show that under the influence of a psychedelic, the default mode network is quieted, while other regions of the brain increase communication with each other. A mathematical model captures a normal brainamp;#39;s activity. In contrast, a brain under the influence of psilocybin reveals a dramatic increase in global communication. Thousands of new connections form, linking brain regions that donamp;#39;t normally talk to each other. - One analogy Iamp;#39;ve used for how psychedelics work in the brain is this snow globe. When you pick up a snow globe you know the snowamp;#39;s settled at the bottom, itamp;#39;s sort of fixed, and then you pick it up, shake it and things jiggle around and thereamp;#39;s randomness and a kind of chaos if you want in the system. - [Narrator] The use
