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exercise training could be looked at as a translational Paradigm uh we found several years ago that if you take animals with heart failure and put them on an exercise training regimen some of these abnormalities that I mentioned earlier such as nitric oxide and super oxide reverse simply by exercising them if we look at the expression of proteins in the central nervous system that produce nitric oxide or super oxide their abnormal levels can be normalized by about a 4-week exercise training in experimental animals turns out that um recent data now show that in humans there is a beneficial effect as well it used to be that if you had heart failure you were bedridden or you were told told not to exert yourself and of course if you have very severe heart failure thatamp;#39;s still the case but thereamp;#39;s a spec of people with heart failure that are still ambulatory and able to do exercise and for those people exercise tends to be very beneficial not only is it beneficial in terms o
