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gel one cross-linked hyaluronic the only three milliliter single injection cross-linked hyaluronate gel that provides safe and effective osteoarthritis pain relief with no reports of pseudosepsis a severe and painful inflammatory reaction prior to administering gel one hyaluronate prepare the injection site and if desired apply local anesthetic the joint space is accessed through the soft palpable anterolateral port that can be felt just lateral to the inferior pole of the patella and the proximal portion of the patella tendon through this anterolateral port aspirate the joint as needed using an 18 to 20 gauge needle and an appropriately sized empty syringe using strict aseptic technique attach the syringe containing gel 1 hyaluronate to an 18 to 20 gauge needle and inject gel 1 through the anterolateral port if aspiration was performed use the already placed needle after gel one hyaluronate is injected into the knee joint cavity it supplements the synovial fluid providing pain relief
