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the most common reason for injection of the first cmc joint is osteoarthritis corticosteroid injection can provide up to four to six months of relief but the duration can be much less depending on the degree of joint damage in this video i will demonstrate the injection of the first cmc joint the first carpal metacarpal or cmc joint is located between the proximal tip of the first metacarpal and the trapezium at the distal border of the anatomic snuff box the snuff box is bordered by the extensor pollicis brevis and abductor pollicis longus tendons on the vola margin and the extensor pollicis longus tendon on the dorsal margin palpate the joint space while flexing and extending the thumb you can use your thumbnail or a retractable pen to mark the joint space for injection remember that the mark may shift as the thumb is flat during the injection the wrist can be supported on a towel rule during the procedure these injections should always be done using sterile precautions a no touch te