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Dr. Rishi Desai from Osmosis discusses three key tips for taking a thorough patient history. He emphasizes understanding the mechanics of gathering a patient history, which includes identifying the chief complaint, the History of Present Illness (HPI), past medical history, medications, allergies, family history, social history, and conducting a review of systems. However, the focus is on enhancing the quality of the interaction. His first tip is to listen well and empathize with the patient, highlighting that while a robot can ask basic questions, the human connection and understanding are crucial in patient care. This sets the stage for building rapport and gathering more meaningful information.