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metformins main pharmacological effect is it is the most controversial drug used for diabetes as well now recently there was a metformin recall does metformin really cause kidney damage what are the metformin alternatives what else can i take besides metformin right metformin was first shown to help diabetics avoid cancer in 2005 whereas early studies show that it affects a wide range of molecular pathways that play a role in the development of almost every type of cancer but other studies show that it works well with a wide range of other anti-cancer treatments like your chemotherapy if you already have cancer your radiotherapy your immunotherapy etc in addition a growing number of clinical studies show that it can help prevent cancers metformins main pharmacological effect is to lower high blood sugar levels as you all know that is mostly because it improves insulin resistance in the liver which is an organ that causes a lot of sugar production in your