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what are ethylglucuronide and ethyl sulfate ethyl glucuronidate and ethyl sulfate are major metabolites of ethanol ethanol being the active ingredient in alcoholic beverages these compounds are formed in the liver by metabolic enzymes and theyre readily detectable in urine specimens following consumption of an alcoholic beverage theyre often measured in drug testing and they serve as a sensitive marker of alcohol intake and one of the questions we often get asked is should i be drug testing for ethanol the parent compound or should i be testing for the metabolites there are advantages and disadvantages to both but the major distinction we usually make is the window of detection of these compounds ethanol has a very short window of detection certainly less than 24 hours in many instances less than that ethyl glucuronide and sulfate can be detected for much longer periods of time depending on the amount of alcohol consumed it could be two three sometimes even longer in terms of days t