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Hi. This is Karen McKee, retired scientist and author with another video about scientific writing. Everyone recognizes the opening sentence of A Tale of Two Cities by Charles Dickens. That beginning makes an indelible first impression and announces that the author is about to unfurl a fascinating story. There are many other great examples of memorable first sentences in the literary world, but the point I want to make is that first sentences, whether in a novel or a scientific paper, are important because they capture the readers attention and set the stage for what comes after. How many times have you sat down to read a journal article and found the opening statement to be uninteresting, uninspiring, or trite? How often do such papers go on to surprise you with their insights? Given the competition for space in journals, authors cannot ignore the fact that they not only need outstanding data, they must write memorable papers. And if they are smart, they will start off with a compe