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prepare the binary solvent manager for operation by performing a seal wash prime and pump prime first remove the seal wash inlet tubing from the solvent reservoir and disconnect the solvent reservoir filter connect the tubing adapter to the syringe fill the syringe with seal wash solution then connect the syringe assembly to the seal wash tubing in the console select binary solvent manager from the system tree click control prime seal wash and then click yes to begin the seal wash priming process push on the syringe plunger to push seal wash solvent through the system when the seal wash solvent is flowing out of the seal wash waste tube click control prime seal wash to stop the priming process remove the syringe and adapter reconnect the filter and replace the seal wash inlet tubing into the seal wash solvent reservoir to prime the binary solvent manager locate the appropriate solvent vent line if you are priming solvent b follow the stainless steel vent line from port 1 on the vent v