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hello my name is Jackie Hutton from clinical trials Ontario in this video you will learn how to request a signature on applications in sitio stream the provincial applicant signature is required on the initial submission of any provincial application in sitio stream with the exception of some administrative amendments the center principal investigator is required to sign off on the initial submission of any Center level application for a site except for some administrative amendments the PA and P I can delegate signing authority to someone on the study team to sign off on the resubmission of any provincial or Center form when you are ready to request a signature enter the navigation tap of the application click on the agreements in approval section this is always the last page of applications in sitio stream the agreements in approval section contains the attestation language that each signatory must agree to before placing their electronic signature on the application a request signa